Description
JAK1-IN-7 is a Janus-associated kinase 1 (JAK1) inhibitor extracted from patent WO2018134213A1, Example 63, has an anti-inflammatory effect.
Product information
CAS Number: 2241039-81-4
Molecular Weight: 599.65
Formula: C28H31F2N7O4S
Chemical Name: (2R)-N-(3-{5-fluoro-2-[(2-fluoro-3-methanesulfonylphenyl)amino]pyrimidin-4-yl}-1H-indol-7-yl)-3-methoxy-2-(4-methylpiperazin-1-yl)propanamide
Smiles: CN1CCN(CC1)[C@H](COC)C(=O)NC1=CC=CC2=C1NC=C2C1=NC(NC2=CC=CC(=C2F)S(C)(=O)=O)=NC=C1F
InChiKey: JNUZADQZHYFJGW-JOCHJYFZSA-N
InChi: InChI=1S/C28H31F2N7O4S/c1-36-10-12-37(13-11-36)22(16-41-2)27(38)33-21-8-4-6-17-18(14-31-26(17)21)25-19(29)15-32-28(35-25)34-20-7-5-9-23(24(20)30)42(3,39)40/h4-9,14-15,22,31H,10-13,16H2,1-3H3,(H,33,38)(H,32,34,35)/t22-/m1/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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