Description
sFTX-3.3 is a Ca2+ channel antagonist with IC50s of approximately 0.24 mM and 0.70 mM against P-type and N-type channels.
Product information
CAS Number: 141997-14-0
Molecular Weight: 287.40
Formula: C12H29N7O
Chemical Name: (2S)-2-amino-N-{3-[(3-aminopropyl)amino]propyl}-5-[(diaminomethylidene)amino]pentanamide
Smiles: NC(N)=NCCC[C@H](N)C(=O)NCCCNCCCN
InChiKey: CHIHEOCAOMXRKN-JTQLQIEISA-N
InChi: InChI=1S/C12H29N7O/c13-5-2-6-17-7-3-9-18-11(20)10(14)4-1-8-19-12(15)16/h10,17H,1-9,13-14H2,(H,18,20)(H4,15,16,19)/t10-/m0/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
sFTX-3.3 (100 μM) reduces the duration of the slow component of presynaptic calcium currents by about 50% of the control and also reduces presynaptic sodium current by approximately 20% of the control. sFTX-3.3 (100 μM) reduces whole-cell sodium current recorded from SK.N.SH cells by approximately 15%.
Products are for research use only. Not for human use.
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