sFTX-3.3


Catalog No. Size PriceQuantity
M28014-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

sFTX-3.3 is a Ca2+ channel antagonist with IC50s of approximately 0.24 mM and 0.70 mM against P-type and N-type channels.

Product information

CAS Number: 141997-14-0

Molecular Weight: 287.40

Formula: C12H29N7O

Chemical Name: (2S)-2-amino-N-{3-[(3-aminopropyl)amino]propyl}-5-[(diaminomethylidene)amino]pentanamide

Smiles: NC(N)=NCCC[C@H](N)C(=O)NCCCNCCCN

InChiKey: CHIHEOCAOMXRKN-JTQLQIEISA-N

InChi: InChI=1S/C12H29N7O/c13-5-2-6-17-7-3-9-18-11(20)10(14)4-1-8-19-12(15)16/h10,17H,1-9,13-14H2,(H,18,20)(H4,15,16,19)/t10-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

sFTX-3.3 (100 μM) reduces the duration of the slow component of presynaptic calcium currents by about 50% of the control and also reduces presynaptic sodium current by approximately 20% of the control. sFTX-3.3 (100 μM) reduces whole-cell sodium current recorded from SK.N.SH cells by approximately 15%.

Products are for research use only. Not for human use.

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