Description
AKR1C3-IN-4 is a potent and selective aldo-keto reductase 1C3 (AKR1C3) inhibitor with an IC50 of 0.56 μM. AKR1C3-IN-4 has the potential for castrate resistant prostate cancer (CRPC) research.
Product information
CAS Number: 1284180-11-5
Molecular Weight: 281.23
Formula: C14H10F3NO2
Chemical Name: 3-{[4-(trifluoromethyl)phenyl]amino}benzoic acid
Smiles: OC(=O)C1=CC(=CC=C1)NC1C=CC(=CC=1)C(F)(F)F
InChiKey: MDZIRNPRVJEHHX-UHFFFAOYSA-N
InChi: InChI=1S/C14H10F3NO2/c15-14(16,17)10-4-6-11(7-5-10)18-12-3-1-2-9(8-12)13(19)20/h1-8,18H,(H,19,20)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
AKR1C3-IN-4 has an IC50 of 15.1 μM for AKR1C2.
Products are for research use only. Not for human use.
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