CDK2-IN-4


Catalog No. Size PriceQuantity
M28422-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

CDK2-IN-4 is a potent and selective CDK2 inhibitor with an IC50 of 44 nM for CDK2/cyclin A, shows 2,000-fold selectivity over CDK1/cyclin B (IC50=86 uM).

Product information

CAS Number: 2079895-42-2

Molecular Weight: 442.49

Formula: C23H18N6O2S

Chemical Name: 4-[(6-{[1,1'-biphenyl]-3-yl}-7H-purin-2-yl)amino]benzene-1-sulfonamide

Smiles: NS(=O)(=O)C1C=CC(=CC=1)NC1N=C2N=CNC2=C(N=1)C1=CC(=CC=C1)C1C=CC=CC=1

InChiKey: FUGRWXRQJGJIER-UHFFFAOYSA-N

InChi: InChI=1S/C23H18N6O2S/c24-32(30,31)19-11-9-18(10-12-19)27-23-28-20(21-22(29-23)26-14-25-21)17-8-4-7-16(13-17)15-5-2-1-3-6-15/h1-14H,(H2,24,30,31)(H2,25,26,27,28,29)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 20.83 mg/mL (47.07 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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