Description
AZ084 is a potent, selective, allosteric and oral active CCR8 antagonist, with a Ki of 0.9 nM. Has potential to treat asthma.
Product information
CAS Number: 929300-19-6
Molecular Weight: 434.57
Formula: C26H34N4O2
Chemical Name: 6-{9-[(2,2-dimethyl-2,3-dihydro-1-benzofuran-4-yl)methyl]-3,9-diazaspiro[5.5]undecane-3-carbonyl}pyridin-3-amine
Smiles: CC1(C)CC2=C(C=CC=C2CN2CCC3(CCN(CC3)C(=O)C3=CC=C(N)C=N3)CC2)O1
InChiKey: WIGFMKMFRGRSDE-UHFFFAOYSA-N
InChi: InChI=1S/C26H34N4O2/c1-25(2)16-21-19(4-3-5-23(21)32-25)18-29-12-8-26(9-13-29)10-14-30(15-11-26)24(31)22-7-6-20(27)17-28-22/h3-7,17H,8-16,18,27H2,1-2H3
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : 250 mg/mL (575.28 mM; Need ultrasonic).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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