Thiol-C10-amide-PEG8


Catalog No. Size PriceQuantity
M28479-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Thiol-C10-amide-PEG8 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 1353948-95-4

Molecular Weight: 569.79

Formula: C27H55NO9S

Chemical Name: N-(23-hydroxy-3,6,9,12,15,18,21-heptaoxatricosan-1-yl)-11-sulfanylundecanamide

Smiles: OCCOCCOCCOCCOCCOCCOCCOCCNC(=O)CCCCCCCCCCS

InChiKey: YSLHYTZEFFDHAM-UHFFFAOYSA-N

InChi: InChI=1S/C27H55NO9S/c29-11-13-32-15-17-34-19-21-36-23-25-37-24-22-35-20-18-33-16-14-31-12-10-28-27(30)9-7-5-3-1-2-4-6-8-26-38/h29,38H,1-26H2,(H,28,30)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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