Description
11-Aminoundecanoic acid is an alkyl chain based PROTAC linker can be used in the synthesis of PROTACs.
Product information
CAS Number: 2432-99-7
Molecular Weight: 201.31
Formula: C11H23NO2
Chemical Name: 11-aminoundecanoic acid
Smiles: NCCCCCCCCCCC(O)=O
InChiKey: GUOSQNAUYHMCRU-UHFFFAOYSA-N
InChi: InChI=1S/C11H23NO2/c12-10-8-6-4-2-1-3-5-7-9-11(13)14/h1-10,12H2,(H,13,14)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : 3.33 mg/mL (16.54 mM; ultrasonic and adjust pH to 2 with HCl). H2O : < 0.1 mg/mL (ultrasonic;adjust pH to 3 with HCl) (insoluble).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Products are for research use only. Not for human use.
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