Description
Propargyl-PEG8-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Product information
CAS Number: 1422540-92-8
Molecular Weight: 424.55
Formula: C19H36O8S
Chemical Name: 3,6,9,12,15,18,21,24-octaoxaheptacos-26-yne-1-thiol
Smiles: C#CCOCCOCCOCCOCCOCCOCCOCCOCCS
InChiKey: IBJAGHUIGLSWBY-UHFFFAOYSA-N
InChi: InChI=1S/C19H36O8S/c1-2-3-20-4-5-21-6-7-22-8-9-23-10-11-24-12-13-25-14-15-26-16-17-27-18-19-28/h1,28H,3-19H2
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Products are for research use only. Not for human use.
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