Boc-11-aminoundecanoic acid


Catalog No. Size PriceQuantity
M28529-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Boc-11-aminoundecanoic acid is an Alkyl/ether-based PROTAC linker can be used in the synthesis of MS432 (HY-130602).

Product information

CAS Number: 10436-25-6

Molecular Weight: 301.42

Formula: C16H31NO4

Chemical Name: 11-{[(tert-butoxy)carbonyl]amino}undecanoic acid

Smiles: CC(C)(C)OC(=O)NCCCCCCCCCCC(O)=O

InChiKey: HPTPZJBSQUULAV-UHFFFAOYSA-N

InChi: InChI=1S/C16H31NO4/c1-16(2,3)21-15(20)17-13-11-9-7-5-4-6-8-10-12-14(18)19/h4-13H2,1-3H3,(H,17,20)(H,18,19)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

MS432 is a first-in-class and highly selective PD0325901-based VHL-recruiting PROTAC degrader for MEK1 and MEK2. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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