Glisoxepide


Catalog No. Size PriceQuantity
M28562-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Glisoxepide, a sulphonamide derivative, is an orally available nonselective K(ATP) channel blocker, with antihyperglycemic activity and cardiovascular regulation effect.

Product information

CAS Number: 25046-79-1

Molecular Weight: 449.52

Formula: C20H27N5O5S

Chemical Name: N-{2-[4-({[(azepan-1-yl)carbamoyl]amino}sulfonyl)phenyl]ethyl}-5-methyl-1,2-oxazole-3-carboxamide

Smiles: CC1=CC(=NO1)C(=O)NCCC1C=CC(=CC=1)S(=O)(=O)NC(=O)NN1CCCCCC1

InChiKey: ZKUDBRCEOBOWLF-UHFFFAOYSA-N

InChi: InChI=1S/C20H27N5O5S/c1-15-14-18(23-30-15)19(26)21-11-10-16-6-8-17(9-7-16)31(28,29)24-20(27)22-25-12-4-2-3-5-13-25/h6-9,14H,2-5,10-13H2,1H3,(H,21,26)(H2,22,24,27)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Glisoxepide inhibits the uptake of bile acids into isolated rat hepatocytes. Glisoxepide noncompetitively inhibits the cholate uptake with a Ki of 200 μM.

Products are for research use only. Not for human use.

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