Description
Acid-PEG5-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Product information
CAS Number: 1309460-29-4
Molecular Weight: 394.46
Formula: C18H34O9
Chemical Name: 19-(tert-butoxy)-19-oxo-4,7,10,13,16-pentaoxanonadecanoic acid
Smiles: CC(C)(C)OC(=O)CCOCCOCCOCCOCCOCCC(O)=O
InChiKey: ILIIUHKWCBCCNI-UHFFFAOYSA-N
InChi: InChI=1S/C18H34O9/c1-18(2,3)27-17(21)5-7-23-9-11-25-13-15-26-14-12-24-10-8-22-6-4-16(19)20/h4-15H2,1-3H3,(H,19,20)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Products are for research use only. Not for human use.
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