Dde Biotin-PEG4-alkyne


Catalog No. Size PriceQuantity
M28571-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Dde Biotin-PEG4-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 1802908-00-4

Molecular Weight: 650.83

Formula: C32H50N4O8S

Chemical Name: 5-[(3aR,4R,6aS)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl]-N-[15-(2-hydroxy-4,4-dimethyl-6-oxocyclohex-1-en-1-yl)-3,6,9,12-tetraoxa-16-azanonadec-15-en-18-yn-1-yl]pentanamide

Smiles: CC1(C)CC(=O)C(=C(O)C1)C(CCOCCOCCOCCOCCNC(=O)CCCC[C@H]1SC[C@H]2NC(=O)N[C@H]21)=NCC#C

InChiKey: BDJHEZRAKBBIJH-YPKZICDUSA-N

InChi: InChI=1S/C32H50N4O8S/c1-4-10-33-23(29-25(37)20-32(2,3)21-26(29)38)9-12-41-14-16-43-18-19-44-17-15-42-13-11-34-28(39)8-6-5-7-27-30-24(22-45-27)35-31(40)36-30/h1,24,27,30,37H,5-22H2,2-3H3,(H,34,39)(H2,35,36,40)/b33-23+/t24-,27-,30-/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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