N-Me-N-bis(PEG4-acid)


Catalog No. Size PriceQuantity
M28643-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

N-Me-N-bis(PEG4-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 2055014-77-0

Molecular Weight: 527.60

Formula: C23H45NO12

Chemical Name: 16-methyl-4,7,10,13,19,22,25,28-octaoxa-16-azahentriacontanedioic acid

Smiles: CN(CCOCCOCCOCCOCCC(O)=O)CCOCCOCCOCCOCCC(O)=O

InChiKey: GVLKSZBFWWZTQF-UHFFFAOYSA-N

InChi: InChI=1S/C23H45NO12/c1-24(4-8-31-12-16-35-20-18-33-14-10-29-6-2-22(25)26)5-9-32-13-17-36-21-19-34-15-11-30-7-3-23(27)28/h2-21H2,1H3,(H,25,26)(H,27,28)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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