Description
Azido-PEG5-CH2CO2-NHS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Product information
CAS Number: 2144777-77-3
Molecular Weight: 418.40
Formula: C16H26N4O9
Chemical Name: 2,5-dioxopyrrolidin-1-yl 17-azido-3,6,9,12,15-pentaoxaheptadecanoate
Smiles: [N-]=[N+]=NCCOCCOCCOCCOCCOCC(=O)ON1C(=O)CCC1=O
InChiKey: PKNZIAMWWCOXMJ-UHFFFAOYSA-N
InChi: InChI=1S/C16H26N4O9/c17-19-18-3-4-24-5-6-25-7-8-26-9-10-27-11-12-28-13-16(23)29-20-14(21)1-2-15(20)22/h1-13H2
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Products are for research use only. Not for human use.
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