POL1-IN-1


Catalog No. Size PriceQuantity
M28671-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

POL1-IN-1 is a RNA polymerase 1 (POL1, also known as Pol I) inhibitor with an IC50 of less than 0.5 uM. POL1-IN-1 inhibits ribosome biogenesis by inhibiting POL1 transcription.

Product information

CAS Number: 1822358-25-7

Molecular Weight: 356.42

Formula: C21H20N6

Chemical Name: 4-[(3R,5S)-3,5-dimethylpiperazin-1-yl]-1,3,11-triazatetracyclo[8.7.0.0²,⁷.0¹²,¹⁷]heptadeca-2,4,6,8,10,12,14,16-octaene-9-carbonitrile

Smiles: C[C@@H]1CN(C[C@H](C)N1)C1=CC=C2C=C(C#N)C3=NC4=CC=CC=C4N3C2=N1

InChiKey: HFQPEPQECNSOFF-OKILXGFUSA-N

InChi: InChI=1S/C21H20N6/c1-13-11-26(12-14(2)23-13)19-8-7-15-9-16(10-22)21-24-17-5-3-4-6-18(17)27(21)20(15)25-19/h3-9,13-14,23H,11-12H2,1-2H3/t13-,14+

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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