PIK-108


Catalog No. Size PriceQuantity
M28712-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

PIK-108 is a non-ATP competitive, allosteric p110β/p110δ selective inhibitor.

Product information

CAS Number: 901398-68-3

Molecular Weight: 364.44

Formula: C22H24N2O3

Chemical Name: 6-methyl-2-(morpholin-4-yl)-8-[1-(phenylamino)ethyl]-4H-chromen-4-one

Smiles: CC1C=C2C(OC(=CC2=O)N2CCOCC2)=C(C=1)C(C)NC1C=CC=CC=1

InChiKey: VRCXIJAYLCUSHC-UHFFFAOYSA-N

InChi: InChI=1S/C22H24N2O3/c1-15-12-18(16(2)23-17-6-4-3-5-7-17)22-19(13-15)20(25)14-21(27-22)24-8-10-26-11-9-24/h3-7,12-14,16,23H,8-11H2,1-2H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 50 mg/mL (137.20 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PIK-108 (0.1-10 μM; 1 hour) blocks phosphorylation of PKB/Akt.

Products are for research use only. Not for human use.

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