H-L-Photo-lysine


Catalog No. Size PriceQuantity
M28761-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

H-L-Photo-lysine is a diazirine-containing lysine amino acid and is a photo-cross-linker. H-L-Photo-lysine can site-selective incorporated into proteins and is used to crosslink protein-protein interactions in vitro and in living cells. H-L-Photo-lysine acts as a UV light-activated photo-crosslinking probe.

Product information

CAS Number: 1253643-88-7

Molecular Weight: 272.30

Formula: C11H20N4O4

Chemical Name: (2S)-2-amino-6-({[2-(3-methyl-3H-diazirin-3-yl)ethoxy]carbonyl}amino)hexanoic acid

Smiles: CC1(CCOC(=O)NCCCC[C@H](N)C(O)=O)N=N1

InChiKey: LUCMNTLJAFTFDU-QMMMGPOBSA-N

InChi: InChI=1S/C11H20N4O4/c1-11(14-15-11)5-7-19-10(18)13-6-3-2-4-8(12)9(16)17/h8H,2-7,12H2,1H3,(H,13,18)(H,16,17)/t8-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 2 mg/mL (7.34 mM; Need ultrasonic). H2O : 5 mg/mL (18.36 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Photo-lysine, which is readily incorporated into proteins by native mammalian translation machinery, can be used to capture and identify proteins that recognize lysine post-translational modifications (PTMs), including 'readers' and 'erasers' of histone modifications.

Products are for research use only. Not for human use.

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