Mal-PEG4-acid


Catalog No. Size PriceQuantity
M29036-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Mal-PEG4-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

Product information

CAS Number: 518044-41-2

Molecular Weight: 345.35

Formula: C15H23NO8

Chemical Name: 1-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3,6,9,12-tetraoxapentadecan-15-oic acid

Smiles: OC(=O)CCOCCOCCOCCOCCN1C(=O)C=CC1=O

InChiKey: BTFZSOVKVDCKQD-UHFFFAOYSA-N

InChi: InChI=1S/C15H23NO8/c17-13-1-2-14(18)16(13)4-6-22-8-10-24-12-11-23-9-7-21-5-3-15(19)20/h1-2H,3-12H2,(H,19,20)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 100 mg/mL (289.56 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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