Description
BnOH-NH-bis-(C2-S)-propane-O-isoprene ester (PROTAC Linker 29) is an alkyl ether-based PROTAC linker can be used in the synthesis of PROTACs.
Product information
CAS Number: 2448704-23-0
Molecular Weight: 397.55
Formula: C19H27NO4S2
Chemical Name: 2-[(2-{[2-(buta-1,3-dien-2-yloxy)ethyl]sulfanyl}propan-2-yl)sulfanyl]ethyl N-[4-(hydroxymethyl)phenyl]carbamate
Smiles: CC(C)(SCCOC(=C)C=C)SCCOC(=O)NC1=CC=C(CO)C=C1
InChiKey: HCWRZUOZWXESHS-UHFFFAOYSA-N
InChi: InChI=1S/C19H27NO4S2/c1-5-15(2)23-10-12-25-19(3,4)26-13-11-24-18(22)20-17-8-6-16(14-21)7-9-17/h5-9,21H,1-2,10-14H2,3-4H3,(H,20,22)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Products are for research use only. Not for human use.
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