Hydroxy-Amino-bis(PEG2-propargyl)


Catalog No. Size PriceQuantity
M29166-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Hydroxy-Amino-bis(PEG2-propargyl) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 2100306-77-0

Molecular Weight: 313.39

Formula: C16H27NO5

Chemical Name: 2-(4,7,13,16-tetraoxa-10-azanonadeca-1,18-diyn-10-yl)ethan-1-ol

Smiles: C#CCOCCOCCN(CCO)CCOCCOCC#C

InChiKey: CFAWPKGCJLYIOW-UHFFFAOYSA-N

InChi: InChI=1S/C16H27NO5/c1-3-9-19-13-15-21-11-6-17(5-8-18)7-12-22-16-14-20-10-4-2/h1-2,18H,5-16H2

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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