Carboxy-PEG4-phosphonic acid ethyl ester


Catalog No. Size PriceQuantity
M29295-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Carboxy-PEG4-phosphonic acid ethyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 1964503-39-6

Molecular Weight: 386.38

Formula: C15H31O9P

Chemical Name: 1-(diethoxyphosphoryl)-3,6,9,12-tetraoxapentadecan-15-oic acid

Smiles: CCOP(=O)(CCOCCOCCOCCOCCC(O)=O)OCC

InChiKey: KCBOZPJXNCOSFU-UHFFFAOYSA-N

InChi: InChI=1S/C15H31O9P/c1-3-23-25(18,24-4-2)14-13-22-12-11-21-10-9-20-8-7-19-6-5-15(16)17/h3-14H2,1-2H3,(H,16,17)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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