Description
DHODH-IN-4 (compound 17) is a human and Plasmodium falciparum dihydroorotate dehydrogenase (DHODH) inhibitor, with IC50 values of 4 μM and 0.18 μM for PfDHODH and HsDHODH, respectively. DHODH-IN-4 (compound 17) possess antimalarial activity.
Product information
CAS Number: 1148125-93-2
Molecular Weight: 347.20
Formula: C17H12Cl2N2O2
Chemical Name: (2Z)-2-cyano-N-{2',3-dichloro-[1,1'-biphenyl]-4-yl}-3-hydroxybut-2-enamide
Smiles: C/C(/O)=C(\C#N)/C(=O)NC1=CC=C(C=C1Cl)C1=CC=CC=C1Cl
InChiKey: KEZXIYKJTYTGOO-RAXLEYEMSA-N
InChi: InChI=1S/C17H12Cl2N2O2/c1-10(22)13(9-20)17(23)21-16-7-6-11(8-15(16)19)12-4-2-3-5-14(12)18/h2-8,22H,1H3,(H,21,23)/b13-10-
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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