CMF019


Catalog No. Size PriceQuantity
M29782-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

CMF019 is a potent and small molecule agonist at Apelin receptor (APJ) with G protein bias. CMF019 binds to APJ with pKi values of 8.58, 8.49 and 8.71 for human, rat, and mouse, respectively. CMF019 mimics the beneficial cardiovascular actions of apelin in rodents. Apelin receptor (APJ) is a G protein-coupled receptor (GPCR) activated by the endogenous peptide apelin.

Product information

CAS Number: 1586787-08-7

Molecular Weight: 455.61

Formula: C25H33N3O3S

Chemical Name: (3S)-5-methyl-3-{[1-(pentan-3-yl)-2-[(thiophen-2-yl)methyl]-1H-1,3-benzodiazol-5-yl]formamido}hexanoic acid

Smiles: CC(C)C[C@@H](CC(O)=O)NC(=O)C1=CC=C2C(=C1)N=C(CC1=CC=CS1)N2C(CC)CC

InChiKey: VCQKKZXFASLXAH-SFHVURJKSA-N

InChi: InChI=1S/C25H33N3O3S/c1-5-19(6-2)28-22-10-9-17(25(31)26-18(12-16(3)4)14-24(29)30)13-21(22)27-23(28)15-20-8-7-11-32-20/h7-11,13,16,18-19H,5-6,12,14-15H2,1-4H3,(H,26,31)(H,29,30)/t18-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

Payment & Security

PayPal Venmo

Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.

You may also like

Recently viewed