Description
Anti-Heart Failure Agent 1 an orally available compound suitable for the treatment of heart failure without inducing nausea, vomiting and restlessness.
Product information
CAS Number: 142648-47-3
Molecular Weight: 270.28
Formula: C11H11FN2O3S
Chemical Name: 4-fluoro-N'-hydroxy-5,6-dimethoxy-1-benzothiophene-2-carboximidamide
Smiles: COC1C(F)=C2C=C(SC2=CC=1OC)C(N)=NO
InChiKey: JHCWLAVFDAPCMI-UHFFFAOYSA-N
InChi: InChI=1S/C11H11FN2O3S/c1-16-6-4-7-5(9(12)10(6)17-2)3-8(18-7)11(13)14-15/h3-4,15H,1-2H3,(H2,13,14)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vivo:
15 mg/kg of compound produces 60% increase in left ventricular contractility in anaesthetized cat. An oral dose of compound (25 mg/kg) could produce marked increases in left ventricular contractility (45%) in conscious dog.
Products are for research use only. Not for human use.
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