Glibornuride


Catalog No. Size PriceQuantity
M30040-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Glibornuride is a blocker of ATP-sensitive K+ channels (KATP channel) with a pKi of 5.75. Antidiabetic agent.

Product information

CAS Number: 26944-48-9

Molecular Weight: 366.48

Formula: C18H26N2O4S

Chemical Name: 3-[(1S,2S,3R,4R)-3-hydroxy-4,7,7-trimethylbicyclo[2.2.1]heptan-2-yl]-1-(4-methylbenzenesulfonyl)urea

Smiles: CC1(C)[C@@H]2CC[C@@]1(C)[C@@H](O)[C@H]2NC(=O)NS(=O)(=O)C1=CC=C(C)C=C1

InChiKey: RMTYNAPTNBJHQI-LLDVTBCESA-N

InChi: InChI=1S/C18H26N2O4S/c1-11-5-7-12(8-6-11)25(23,24)20-16(22)19-14-13-9-10-18(4,15(14)21)17(13,2)3/h5-8,13-15,21H,9-10H2,1-4H3,(H2,19,20,22)/t13-,14+,15+,18+/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vivo:

Administration of Glibornuride (5 mg/kg; gavage, daily for 28 days) for 28 days causes an increase in body weights in the diabetic groups in Swiss albino rats. Treatment with Glibornuride for 28 days decreases the serum uric acid levels in diabetic rats. Administration of Glibornuride for 28 days, insignificantly increases the liver lipid peroxidation levels in diabetic rats.

Products are for research use only. Not for human use.

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