Description
(±)-LY367385 is the racemate of LY367385. LY367385 is a highly potent and selective mGluR1a antagonist. LY367385 has an IC50 of 8.8 μM for inhibits of quisqualate-induced phosphoinositide (PI) hydrolysis, compared with > 100 μM for mGlu5a.
Product information
CAS Number: 198419-90-8
Molecular Weight: 209.20
Formula: C10H11NO4
Chemical Name: 4-[amino(carboxy)methyl]-3-methylbenzoic acid
Smiles: CC1=CC(=CC=C1C(N)C(O)=O)C(O)=O
InChiKey: SGIKDIUCJAUSRD-UHFFFAOYSA-N
InChi: InChI=1S/C10H11NO4/c1-5-4-6(9(12)13)2-3-7(5)8(11)10(14)15/h2-4,8H,11H2,1H3,(H,12,13)(H,14,15)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: H2O : 5.56 mg/mL (26.58 mM; ultrasonic and warming and heat to 60°C).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vivo:
mGluR1a拮抗剂
Products are for research use only. Not for human use.
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