Carboxyebselen


Catalog No. Size PriceQuantity
M30119-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Carboxyebselen (HOOC-Ebs) is a potent and selective inhibitor of endothelial nitric oxide synthase (eNOS).

Product information

CAS Number: 153871-75-1

Molecular Weight: 318.19

Formula: C14H9NO3Se

Chemical Name: 4-(3-oxo-2,3-dihydro-1,2-benzoselenazol-2-yl)benzoic acid

Smiles: OC(=O)C1C=CC(=CC=1)N1[Se]C2=CC=CC=C2C1=O

InChiKey: FOEPTYDLLXMPLJ-UHFFFAOYSA-N

InChi: InChI=1S/C14H9NO3Se/c16-13-11-3-1-2-4-12(11)19-15(13)10-7-5-9(6-8-10)14(17)18/h1-8H,(H,17,18)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vivo:

Carboxyebselen (HOOC-Ebs), a derivative of Ebselen (Ebs) inhibits NOS present in enzymatic preparations from bovine endothelium, porcine cerebella, and murine spleen, however, it is both more potent and more selective for the constitutive endothelial NOS than Ebs. Unlike Ebs, HOOC-Ebs (0.1-30 microM) causes a concentration-dependent endothelium-independent relaxations of rings of rabbit aorta.

Products are for research use only. Not for human use.

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