Description
Ezetimibe phenoxy glucuronide-D4 (Ezetimibe glucuronide-D4) is the deuterium labeled Ezetimibe phenoxy glucuronide. Ezetimibe phenoxy glucuronide is the active metabolite of Ezetimibe. Antihyperlipoproteinemic activity. Ezetimibe is a potent cholesterol absorption inhibitor.
Product information
CAS Number: 1426174-41-5
Molecular Weight: 589.57
Formula: C30H29F2NO9
Chemical Name: (2S,3S,4S,5R,6S)-6-{4-[(2S,3R)-1-[4-fluoro(2,3,5,6-²H₄)phenyl]-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-oxoazetidin-2-yl]phenoxy}-3,4,5-trihydroxyoxane-2-carboxylic acid
Smiles: [2H]C1=C(C([2H])=C([2H])C(F)=C1[2H])N1[C@@H]([C@@H](CC[C@H](O)C2C=CC(F)=CC=2)C1=O)C1C=CC(=CC=1)O[C@@H]1O[C@@H]([C@@H](O)[C@H](O)[C@H]1O)C(O)=O
InChiKey: UOFYCFMTERCNEW-MKSNJYNSSA-N
InChi: InChI=1S/C30H29F2NO9/c31-17-5-1-15(2-6-17)22(34)14-13-21-23(33(28(21)38)19-9-7-18(32)8-10-19)16-3-11-20(12-4-16)41-30-26(37)24(35)25(36)27(42-30)29(39)40/h1-12,21-27,30,34-37H,13-14H2,(H,39,40)/t21-,22+,23-,24+,25+,26-,27+,30-/m1/s1/i7D,8D,9D,10D
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vivo:
After oral administration, Ezetimibe is absorbed in the small intestine and more than 80% of Ezetimibe metabolized to Ezetimibe Glucuronide.
Products are for research use only. Not for human use.
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