Description
HGPR91 antagonist 1 is a potent and selective small molecule hGPR91 antagonist with an IC50 of 7 μM.
Product information
CAS Number: 1314796-00-3
Molecular Weight: 529.53
Formula: C31H23F4N3O
Chemical Name: N-[(1S)-1-[4'-fluoro-3'-(trifluoromethyl)-[1,1'-biphenyl]-4-yl]ethyl]-2-[4-(1,8-naphthyridin-2-yl)phenyl]acetamide
Smiles: C[C@H](NC(=O)CC1C=CC(=CC=1)C1=CC=C2C=CC=NC2=N1)C1C=CC(=CC=1)C1=CC=C(F)C(=C1)C(F)(F)F
InChiKey: SSQLYMLUWZAJTK-IBGZPJMESA-N
InChi: InChI=1S/C31H23F4N3O/c1-19(21-8-10-22(11-9-21)25-12-14-27(32)26(18-25)31(33,34)35)37-29(39)17-20-4-6-23(7-5-20)28-15-13-24-3-2-16-36-30(24)38-28/h2-16,18-19H,17H2,1H3,(H,37,39)/t19-/m0/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vivo:
HGPR91 antagonist 1 leads to 59, 76% inhibition of ΔMAP at 2, 4 hours and has shown rat plasma protein binding 99%. HGPR91 antagonist 1 has engaged the target under the in vivo condition. HGPR91 antagonist 1 has clearance (CL) of 0.2 nmol/min/mg of RLM.
Products are for research use only. Not for human use.
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