DRI-C21045


Catalog No. Size PriceQuantity
M30327-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

DRI-C21045 (compound 10) is a potent and selective inhibitor of the CD40-CD40L costimulatory protein-protein interaction (PPI) with an IC50 of 0.17 µM. DRI-C21045 shows concentration-dependent inhibition of the activation of NF-κB and B cell proliferation all induced by CD40L with IC50s of 17.1 µM and 4.5 µM, respectively.

Product information

CAS Number: 2101765-81-3

Molecular Weight: 580.61

Formula: C32H24N2O7S

Chemical Name: 8-{4'-[4-(methoxycarbonyl)benzamido]-[1,1'-biphenyl]-4-amido}naphthalene-1-sulfonic acid

Smiles: COC(=O)C1C=CC(=CC=1)C(=O)NC1C=CC(=CC=1)C1C=CC(=CC=1)C(=O)NC1=CC=CC2=CC=CC(=C21)S(O)(=O)=O

InChiKey: BZAWLSZPOBGURT-UHFFFAOYSA-N

InChi: InChI=1S/C32H24N2O7S/c1-41-32(37)25-14-12-23(13-15-25)30(35)33-26-18-16-21(17-19-26)20-8-10-24(11-9-20)31(36)34-27-6-2-4-22-5-3-7-28(29(22)27)42(38,39)40/h2-19H,1H3,(H,33,35)(H,34,36)(H,38,39,40)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 2 mg/mL (3.44 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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