BCL6-IN-4


Catalog No. Size PriceQuantity
M30382-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

BCL6-IN-4 is a potent B-cell lymphoma 6 (BCL6) inhibitor with an IC50 of 97 nM. BCL6-IN-4 has anti-tumor activities.

Product information

CAS Number: 2253879-65-9

Molecular Weight: 503.04

Formula: C25H35ClN6O3

Chemical Name: 5-{[5-chloro-2-(2,2,6,6-tetramethylmorpholin-4-yl)pyrimidin-4-yl]amino}-3-(3-hydroxy-3-methylbutyl)-1-methyl-2,3-dihydro-1H-1,3-benzodiazol-2-one

Smiles: CN1C(=O)N(CCC(C)(C)O)C2=CC(=CC=C12)NC1=NC(=NC=C1Cl)N1CC(C)(C)OC(C)(C)C1

InChiKey: BGCPLWWYPZAURQ-UHFFFAOYSA-N

InChi: InChI=1S/C25H35ClN6O3/c1-23(2,34)10-11-32-19-12-16(8-9-18(19)30(7)22(32)33)28-20-17(26)13-27-21(29-20)31-14-24(3,4)35-25(5,6)15-31/h8-9,12-13,34H,10-11,14-15H2,1-7H3,(H,27,28,29)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 73.33 mg/mL (145.77 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

BCL6-IN-4 (compound 25b) inhibits OCI-Ly1 and OCI-Ly3 cell lines growth with GI50 values of 2.8 μM and 4.2 μM, respectively.

Products are for research use only. Not for human use.

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