Amino-PEG4-C1-Boc


Catalog No. Size PriceQuantity
M30470-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Amino-PEG4-C1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 864680-64-8

Molecular Weight: 307.38

Formula: C14H29NO6

Chemical Name: tert-butyl 14-amino-3,6,9,12-tetraoxatetradecanoate

Smiles: CC(C)(C)OC(=O)COCCOCCOCCOCCN

InChiKey: WPWIGTOQNITKON-UHFFFAOYSA-N

InChi: InChI=1S/C14H29NO6/c1-14(2,3)21-13(16)12-20-11-10-19-9-8-18-7-6-17-5-4-15/h4-12,15H2,1-3H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 20 mg/mL (65.07 mM; Need ultrasonic). H2O : 50 mg/mL (162.67 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins

Products are for research use only. Not for human use.

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