Description
J30-8 is a potent and isoform-selective inhibitor of c-Jun N-terminal kinase 3 (JNK3) with an IC50 of 40 nM, which 2500-fold isoform selectivity against JNK1α1 and JNK2α2. J30-8 exhibits neuroprotective activity in vitro and potential for the treatment of neurodegenerative diseases.
Product information
CAS Number: 2366255-71-0
Molecular Weight: 373.79
Formula: C17H9ClFN3O2S
Chemical Name: 3-{2-[(2-chlorophenyl)amino]-4-hydroxy-1,3-thiazol-5-yl}-5-fluoro-2H-indol-2-one
Smiles: OC1N=C(NC2=CC=CC=C2Cl)SC=1C1C(=O)N=C2C=CC(F)=CC2=1
InChiKey: BDCJVPSBCYWSSS-UHFFFAOYSA-N
InChi: InChI=1S/C17H9ClFN3O2S/c18-10-3-1-2-4-12(10)21-17-22-16(24)14(25-17)13-9-7-8(19)5-6-11(9)20-15(13)23/h1-7,24H,(H,21,22)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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