DU717


Catalog No. Size PriceQuantity
M31835-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

DU-717 is an antihypertensive agent.

Product information

CAS Number: 59943-31-6

Molecular Weight: 314.79

Formula: C12H15ClN4O2S

Chemical Name: 7-chloro-3-(4-methylpiperazin-1-yl)-4H-1λ⁶,2,4-benzothiadiazine-1,1-dione

Smiles: CN1CCN(CC1)C1NC2=CC=C(Cl)C=C2S(=O)(=O)N=1

InChiKey: JPZVJONKWYICFB-UHFFFAOYSA-N

InChi: InChI=1S/C12H15ClN4O2S/c1-16-4-6-17(7-5-16)12-14-10-3-2-9(13)8-11(10)20(18,19)15-12/h2-3,8H,4-7H2,1H3,(H,14,15)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vivo:

A gas chromatographic method has been developed which enables accurate determination of a new antihypertensive agent, DU-717, in plasma. Accurate determinations are possible over a concentration range from 10 to 150 ng/mL of DU-717 in plasma at a relative standard deviation of 6.2%. The minimum detectable concentration is 1 ng/mL. Plasma levels of DU-717 in spontaneously hypertensive and normotensive rats following single oral administrations (10 mg/kg) have also been determined.

Products are for research use only. Not for human use.

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