Description
DU-717 is an antihypertensive agent.
Product information
CAS Number: 59943-31-6
Molecular Weight: 314.79
Formula: C12H15ClN4O2S
Chemical Name: 7-chloro-3-(4-methylpiperazin-1-yl)-4H-1λ⁶,2,4-benzothiadiazine-1,1-dione
Smiles: CN1CCN(CC1)C1NC2=CC=C(Cl)C=C2S(=O)(=O)N=1
InChiKey: JPZVJONKWYICFB-UHFFFAOYSA-N
InChi: InChI=1S/C12H15ClN4O2S/c1-16-4-6-17(7-5-16)12-14-10-3-2-9(13)8-11(10)20(18,19)15-12/h2-3,8H,4-7H2,1H3,(H,14,15)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vivo:
A gas chromatographic method has been developed which enables accurate determination of a new antihypertensive agent, DU-717, in plasma. Accurate determinations are possible over a concentration range from 10 to 150 ng/mL of DU-717 in plasma at a relative standard deviation of 6.2%. The minimum detectable concentration is 1 ng/mL. Plasma levels of DU-717 in spontaneously hypertensive and normotensive rats following single oral administrations (10 mg/kg) have also been determined.
Products are for research use only. Not for human use.
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