Description
Duoperone is a neuroleptic agent and also a antiemetic agent in animal models.
Product information
CAS Number: 62030-88-0
Molecular Weight: 514.58
Formula: C28H26F4N2OS
Chemical Name: 10-{3-[4-(4-fluorobenzoyl)piperidin-1-yl]propyl}-2-(trifluoromethyl)-10H-phenothiazine
Smiles: O=C(C1CCN(CCCN2C3=CC(=CC=C3SC3=CC=CC=C23)C(F)(F)F)CC1)C1=CC=C(F)C=C1
InChiKey: XMUZRUCADGTCPX-UHFFFAOYSA-N
InChi: InChI=1S/C28H26F4N2OS/c29-22-9-6-19(7-10-22)27(35)20-12-16-33(17-13-20)14-3-15-34-23-4-1-2-5-25(23)36-26-11-8-21(18-24(26)34)28(30,31)32/h1-2,4-11,18,20H,3,12-17H2
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vivo:
Duoperone blocks d-amphetamine lethality in mice under aggregated conditions when the pretreatment interval is between one hour and seven days. ABR-6646 produces catalepsy in rats. The onset of this effect is delayed and the duration is prolonged when compared with that of chlorpromazine. Apomorphine-induced pivoting in mice with unilateral lesions of the caudate nucleus is suppressed by ARR-6646.
Products are for research use only. Not for human use.
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