Description
Catalponol is a naphthoquinone derivative. Catalponol enhances dopamine biosynthesis by inducing tyrosine hydroxylase activity. Catalponol also increases the levels of cAMP and tyrosine hydroxylase phosphorylation in PC12 cells.
Product information
CAS Number: 34168-56-4
Molecular Weight: 230.30
Formula: C15H18O2
Chemical Name: (2R,4S)-4-hydroxy-2-(3-methylbut-2-en-1-yl)-1,2,3,4-tetrahydronaphthalen-1-one
Smiles: CC(C)=CC[C@@H]1C[C@H](O)C2=CC=CC=C2C1=O
InChiKey: BTQXIESSQVRLCV-RISCZKNCSA-N
InChi: InChI=1S/C15H18O2/c1-10(2)7-8-11-9-14(16)12-5-3-4-6-13(12)15(11)17/h3-7,11,14,16H,8-9H2,1-2H3/t11-,14+/m1/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
In RAW 264.7 macrophage cells, Catalponol exhibits potent inhibitory effects with an IC50 value of 9.8 µM for inhibiting LPS-induced NO production.
Products are for research use only. Not for human use.
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