Description
endo-BCN-PEG4-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
Product information
CAS Number: 1421932-54-8
Molecular Weight: 441.52
Formula: C22H35NO8
Chemical Name: 1-{[({bicyclo[6.1.0]non-4-yn-9-yl}methoxy)carbonyl]amino}-3,6,9,12-tetraoxapentadecan-15-oic acid
Smiles: OC(=O)CCOCCOCCOCCOCCNC(=O)OCC1C2CCC#CCCC21
InChiKey: MOPSTLKSTPBGBX-UHFFFAOYSA-N
InChi: InChI=1S/C22H35NO8/c24-21(25)7-9-27-11-13-29-15-16-30-14-12-28-10-8-23-22(26)31-17-20-18-5-3-1-2-4-6-19(18)20/h18-20H,3-17H2,(H,23,26)(H,24,25)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Products are for research use only. Not for human use.
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