Azido-PEG1-CH2COO-Cl


Catalog No. Size PriceQuantity
M32132-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Azido-PEG1-CH2COO-Cl (compound 43a) is an alkyl/ether-based PROTAC linker. Azido-PEG1-CH2COO-Cl can be used in the synthesis of PROTAC BRD4 Degrader-1 (HY-133131).

Product information

CAS Number: 79598-49-5

Molecular Weight: 163.56

Formula: C4H6ClN3O2

Chemical Name: 2-(2-azidoethoxy)acetyl chloride

Smiles: [N-]=[N+]=NCCOCC(=O)Cl

InChiKey: FSOUWBZLOHCVTL-UHFFFAOYSA-N

InChi: InChI=1S/C4H6ClN3O2/c5-4(9)3-10-2-1-7-8-6/h1-3H2

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTAC BRD4 Degrader-1 is an efficacious BRD4 degrader with an IC50 of 41.8 nM against BRD4 BD1. PROTAC BRD4 Degrader-1 can effectively degrade BRD4 protein and suppress c-Myc expression.

Products are for research use only. Not for human use.

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