Description
Boc-N-Amido-PEG5-Ms is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Product information
CAS Number: 2128735-28-2
Molecular Weight: 415.50
Formula: C16H33NO9S
Chemical Name: tert-butyl N-[14-(methanesulfonyloxy)-3,6,9,12-tetraoxatetradecan-1-yl]carbamate
Smiles: CC(C)(C)OC(=O)NCCOCCOCCOCCOCCOS(C)(=O)=O
InChiKey: XAHYLBKEJWWORN-UHFFFAOYSA-N
InChi: InChI=1S/C16H33NO9S/c1-16(2,3)26-15(18)17-5-6-21-7-8-22-9-10-23-11-12-24-13-14-25-27(4,19)20/h5-14H2,1-4H3,(H,17,18)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Products are for research use only. Not for human use.
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