Robinetin


Catalog No. Size PriceQuantity
M32220-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Robinetin (3,3',4',5',7-Pentahydroxyflavone), a naturally occurring flavonoid with remarkable ‘two color’ intrinsic fluorescence properties, has antifungal, antiviral, antibacterial, antimutagenesis, and antioxidant activity. Robinetin also can inhibit lipid peroxidation and protein glycosylation.

Product information

CAS Number: 490-31-3

Molecular Weight: 302.24

Formula: C15H10O7

Chemical Name: 3,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-chromen-4-one

Smiles: OC1C=C(C=C(O)C=1O)C1OC2=CC(O)=CC=C2C(=O)C=1O

InChiKey: SOEDEYVDCDYMMH-UHFFFAOYSA-N

InChi: InChI=1S/C15H10O7/c16-7-1-2-8-11(5-7)22-15(14(21)12(8)19)6-3-9(17)13(20)10(18)4-6/h1-5,16-18,20-21H

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 120 mg/mL (397.04 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Robinetin (0.1-10 μM; 1 h) inhibits HIV integrase cleavage and integration in a dose-dependent manner. Robinetin inhibits the DNA synthesis in Proteus vulgaris, and the RNA synthesis in S. aureus. Robinetin (100-200 or 25 μM; 1 or 72 h) inhibits egg yolk phosphatidylcholine (EYPC) membrane lipid peroxidation and hemoglobin A (HbA) glycosylation with high efficiency. Robinetin exhibits photo-induced excited-state intramolecular proton transfer resulting in ‘two color’ (in ‘blue-violet’ and ‘yellow-green’ regions) fluorescence characteristic of flavonols, the relative contributions between the two colors being strongly modulated by the local environment of the fluorophore.

Products are for research use only. Not for human use.

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