Bis-Tos-(2-hydroxyethyl disulfide)


Catalog No. Size PriceQuantity
M32225-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Bis-Tos-(2-hydroxyethyl disulfide) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

Product information

CAS Number: 69981-39-1

Molecular Weight: 462.62

Formula: C18H22O6S4

Chemical Name: 2-({2-[(4-methylbenzenesulfonyl)oxy]ethyl}disulfanyl)ethyl 4-methylbenzene-1-sulfonate

Smiles: CC1C=CC(=CC=1)S(=O)(=O)OCCSSCCOS(=O)(=O)C1C=CC(C)=CC=1

InChiKey: BBGVCMPJFAYXLJ-UHFFFAOYSA-N

InChi: InChI=1S/C18H22O6S4/c1-15-3-7-17(8-4-15)27(19,20)23-11-13-25-26-14-12-24-28(21,22)18-9-5-16(2)6-10-18/h3-10H,11-14H2,1-2H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

Products are for research use only. Not for human use.

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