Description
Propargyl-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Product information
CAS Number: 932741-18-9
Molecular Weight: 213.23
Formula: C9H15N3O3
Chemical Name: 1-azido-2-{2-[2-(prop-2-yn-1-yloxy)ethoxy]ethoxy}ethane
Smiles: C#CCOCCOCCOCCN=[N+]=[N-]
InChiKey: KHDVJPZKKSKIPQ-UHFFFAOYSA-N
InChi: InChI=1S/C9H15N3O3/c1-2-4-13-6-8-15-9-7-14-5-3-11-12-10/h1H,3-9H2
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Products are for research use only. Not for human use.
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