Description
Bromo-PEG1-NH2 hydrobromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Product information
CAS Number: 2287287-20-9
Molecular Weight: 248.94
Formula: C4H11Br2NO
Chemical Name: 2-(2-bromoethoxy)ethan-1-amine hydrobromide
Smiles: Br.NCCOCCBr
InChiKey: VYSWRGGDSXELHO-UHFFFAOYSA-N
InChi: InChI=1S/C4H10BrNO.BrH/c5-1-3-7-4-2-6;/h1-4,6H2;1H
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Products are for research use only. Not for human use.
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