Description
Guaijaverin is a urease inhibitor with an IC50 of 120 μM. Guaijaverin shows antioxidant and anti-Streptococcus mutans activities.
Product information
CAS Number: 22255-13-6
Molecular Weight: 434.35
Formula: C20H18O11
Chemical Name: 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-{[(2S,3R,4S,5S)-3,4,5-trihydroxyoxan-2-yl]oxy}-4H-chromen-4-one
Smiles: OC1C=C(O)C2C(=O)C(O[C@@H]3OC[C@H](O)[C@H](O)[C@H]3O)=C(OC=2C=1)C1=CC(O)=C(O)C=C1
InChiKey: PZZRDJXEMZMZFD-IEGSVRCHSA-N
InChi: InChI=1S/C20H18O11/c21-8-4-11(24)14-13(5-8)30-18(7-1-2-9(22)10(23)3-7)19(16(14)27)31-20-17(28)15(26)12(25)6-29-20/h1-5,12,15,17,20-26,28H,6H2/t12-,15-,17+,20-/m0/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : 100 mg/mL (230.23 mM; Need ultrasonic).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
Guaijaverin has anti-Strep.mutans activity, with MIC values of 4 and 2 mg/ml for MTCC 1943 and CLSM 001 strain of Strep. mutans, respectively.
Products are for research use only. Not for human use.
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