Description
DMAC-SPDB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
Product information
CAS Number: 663599-05-1
Molecular Weight: 397.47
Formula: C16H19N3O5S2
Chemical Name: 2,5-dioxopyrrolidin-1-yl 4-{[5-(dimethylcarbamoyl)pyridin-2-yl]disulfanyl}butanoate
Smiles: CN(C)C(=O)C1=CN=C(C=C1)SSCCCC(=O)ON1C(=O)CCC1=O
InChiKey: XDZYHHAHYBOELZ-UHFFFAOYSA-N
InChi: InChI=1S/C16H19N3O5S2/c1-18(2)16(23)11-5-6-12(17-10-11)26-25-9-3-4-15(22)24-19-13(20)7-8-14(19)21/h5-6,10H,3-4,7-9H2,1-2H3
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
Products are for research use only. Not for human use.
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