DMAC-SPDB


Catalog No. Size PriceQuantity
M32314-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

DMAC-SPDB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

Product information

CAS Number: 663599-05-1

Molecular Weight: 397.47

Formula: C16H19N3O5S2

Chemical Name: 2,5-dioxopyrrolidin-1-yl 4-{[5-(dimethylcarbamoyl)pyridin-2-yl]disulfanyl}butanoate

Smiles: CN(C)C(=O)C1=CN=C(C=C1)SSCCCC(=O)ON1C(=O)CCC1=O

InChiKey: XDZYHHAHYBOELZ-UHFFFAOYSA-N

InChi: InChI=1S/C16H19N3O5S2/c1-18(2)16(23)11-5-6-12(17-10-11)26-25-9-3-4-15(22)24-19-13(20)7-8-14(19)21/h5-6,10H,3-4,7-9H2,1-2H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

Products are for research use only. Not for human use.

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