Description
Azide-PEG2-Ms is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Product information
CAS Number: 176520-23-3
Molecular Weight: 209.22
Formula: C5H11N3O4S
Chemical Name: 2-(2-azidoethoxy)ethyl methanesulfonate
Smiles: CS(=O)(=O)OCCOCCN=[N+]=[N-]
InChiKey: WDDYPDGUFZTNJJ-UHFFFAOYSA-N
InChi: InChI=1S/C5H11N3O4S/c1-13(9,10)12-5-4-11-3-2-7-8-6/h2-5H2,1H3
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Products are for research use only. Not for human use.
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