Azide-PEG3-Sulfone-PEG3-azide


Catalog No. Size PriceQuantity
M32393-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Azide-PEG3-Sulfone-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 2055024-45-6

Molecular Weight: 468.53

Formula: C16H32N6O8S

Chemical Name: 1-[2-(2-azidoethoxy)ethoxy]-2-[2-(2-{2-[2-(2-azidoethoxy)ethoxy]ethoxy}ethanesulfonyl)ethoxy]ethane

Smiles: [N-]=[N+]=NCCOCCOCCOCCS(=O)(=O)CCOCCOCCOCCN=[N+]=[N-]

InChiKey: RBTZRBCQVZHOFS-UHFFFAOYSA-N

InChi: InChI=1S/C16H32N6O8S/c17-21-19-1-3-25-5-7-27-9-11-29-13-15-31(23,24)16-14-30-12-10-28-8-6-26-4-2-20-22-18/h1-16H2

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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