Lipoamido-PEG8-acid


Catalog No. Size PriceQuantity
M32404-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Lipoamido-PEG8-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 1334172-70-1

Molecular Weight: 629.82

Formula: C27H51NO11S2

Chemical Name: 1-[5-(1,2-dithiolan-3-yl)pentanamido]-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oic acid

Smiles: OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)CCCCC1CCSS1

InChiKey: ZIKXLXWMWZSKAA-UHFFFAOYSA-N

InChi: InChI=1S/C27H51NO11S2/c29-26(4-2-1-3-25-6-24-40-41-25)28-7-9-33-11-13-35-15-17-37-19-21-39-23-22-38-20-18-36-16-14-34-12-10-32-8-5-27(30)31/h25H,1-24H2,(H,28,29)(H,30,31)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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