Description
Gly-PEG3-endo-BCN is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Product information
CAS Number: 2354291-37-3
Molecular Weight: 453.57
Formula: C23H39N3O6
Chemical Name: [(1R,8S)-bicyclo[6.1.0]non-4-yn-9-yl]methyl N-[3-(2-{2-[3-(2-aminoacetamido)propoxy]ethoxy}ethoxy)propyl]carbamate
Smiles: NCC(=O)NCCCOCCOCCOCCCNC(=O)OCC1[C@H]2CCC#CCC[C@H]21
InChiKey: MZZHRBCWKALCAE-WCRBZPEASA-N
InChi: InChI=1S/C23H39N3O6/c24-17-22(27)25-9-5-11-29-13-15-31-16-14-30-12-6-10-26-23(28)32-18-21-19-7-3-1-2-4-8-20(19)21/h19-21H,3-18,24H2,(H,25,27)(H,26,28)/t19-,20+,21?
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Products are for research use only. Not for human use.
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