Description
Propargyl-PEG1-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Product information
CAS Number: 119096-95-6
Molecular Weight: 184.23
Formula: C10H16O3
Chemical Name: 2-[2-(prop-2-yn-1-yloxy)ethoxy]oxane
Smiles: C#CCOCCOC1CCCCO1
InChiKey: FIYFSKXDDBZITM-UHFFFAOYSA-N
InChi: InChI=1S/C10H16O3/c1-2-6-11-8-9-13-10-5-3-4-7-12-10/h1,10H,3-9H2
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Products are for research use only. Not for human use.
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